Publications
Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion.
Chen WL, Barszczyk A, Turlova E, Deurloo M, Liu B, Yang BB, Rutka JT, Feng ZP, Sun HS.
Oncotarget. 2015 Apr 19. [ePub ahead of print]
PMID: 25965832
Xyloketal B suppresses glioblastoma cell proliferation and migration in vitro through inhibiting TRPM7-regulated PI3K/Akt and MEK/ERK signaling pathways.
Chen WL, Turlova E, Sun CL, Kim JS, Huang S, Zhong X, Guan YY, Wang GL, Rutka JT, Feng ZP, Sun HS.
Mar Drugs. 2015 Apr 22;13(4):2505-25.
PMID: 25913706
TRPM7 inhibitor carvacrol protects brain from neonatal hypoxic-ischemic injury.
Chen W, Xu B, Xiao A, Liu L, Fang X, Liu R, Turlova E, Barszczyk A, Zhong X, Sun CL, Britto LR, Feng ZP, Sun HS.
Mol Brain. 2015 Feb 19;8:11.
PMID: 25761704
Marine compound xyloketal B reduces neonatal hypoxic-ischemic brain injury.
Xiao AJ, Chen W, Xu B, Liu R, Turlova E, Barszczyk A, Sun CL, Liu L, Deurloo M, Wang GL, Feng ZP, Sun HS.
Mar Drugs. 2014 Dec 24;13(1):29-47.
PMID: 25546517
Collaborators
Hong-Shuo Sun
Milton Charlton
Qinghua Wang
Herbert Gaisano
Shuzo Sugita
John Roder
Peter Backx
Zhaolei Zhang
Renke Li
Terry Snutch
Bob French
Hwa-Sup Shin
Guus Smit
Ronald van Kesteran
TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons.
Turlova E, Bae CY, Deurloo M, Chen W, Barszczyk A, Horgen FD, Fleig A, Feng ZP, Sun HS.
Mol Neurobiol. 2014 Dec 11.
PMID: 25502295
2010 - present
Neuronal K(ATP) channels mediate hypoxic preconditioning and reduce subsequent neonatal hypoxic-ischemic brain injury.
Sun HS, Xu B, Chen W, Xiao A, Turlova E, Alibraham A, Barszczyk A, Bae CY, Quan Y, Liu B, Pei L, Sun CL, Deurloo M, Feng ZP.
Exp Neurol. 2015 Jan;263:161-71.
PMID: 25448006
2010 - present
The nerve growth factor signaling and its potential as therapeutic target for glaucoma.
Wang H, Wang R, Thrimawithana T, Little PJ, Xu J, Feng ZP, Zheng W.
Biomed Res Int. 2014;2014:759473.
PMID: 25250333
Phosphatidylinositol 4,5-biphosphate (PIP2) modulates syntaxin-1A binding to sulfonylurea receptor 2A to regulate cardiac ATP-sensitive potassium (KATP) channels.
Xie L, Liang T, Kang Y, Lin X, Sobbi R, Xie H, Chao C, Backx P, Feng ZP, Shyng SL, Gaisano HY.
J Mol Cell Cardiol. 2014 Oct;75:100-10.
PMID: 25073062
GABA promotes human β-cell proliferation and modulates glucose homeostasis.
Purwana I, Zheng J, Li X, Deurloo M, Son DO, Zhang Z, Liang C, Shen E, Tadkase A, Feng ZP, Li Y, Hasilo C, Paraskevas S, Bortell R, Greiner DL, Atkinson M, Prud'homme GJ, Wang Q.
Diabetes. 2014 Dec;63(12):4197-205.
PMID: 25008178
Differential roles of the mevalonate pathway in the development and survival of mouse purkinje cells in culture.
Barszczyk A, Sun HS, Quan Y, Zheng W, Charlton MP, Feng ZP.
Mol Neurobiol. 2015 Jun;51(3):1116-29.
PMID: 24973985
Efficient experimental design and analysis of real-time PCR assays.
Hui K, Feng ZP.
Channels (Austin). 2013 May-Jun;7(3):160-70.
PMID: 23510941
Dietary salt intake and stroke.
Turlova E, Feng ZP.
Acta Pharmacol Sin. 2013 Jan;34(1):8-9.
PMID: 23274412
The good and bad of microglia/macrophages: new hope in stroke therapeutics.
Huang YC, Feng ZP.
Acta Pharmacol Sin. 2013 Jan;34(1):6-7.
PMID: 23262666
Neuroprotective role of ATP-sensitive potassium channels in cerebral ischemia.
Sun HS, Feng ZP.
Acta Pharmacol Sin. 2013 Jan;34(1):24-32.
PMID: 23123646
In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion.
Huang YC, Rupnik MS, Karimian N, Herrera PL, Gilon P, Feng ZP, Gaisano HY.
Diabetes. 2013 Feb;62(2):519-30.
PMID: 23043159
NALCN: a regulator of pacemaker activity.
Lu TZ, Feng ZP.
Mol Neurobiol. 2012 Jun;45(3):415-23.
PMID: 22476981
Identification of the role of C/EBP in neurite regeneration following microarray analysis of a L. stagnalis CNS injury model.
Aleksic M, Feng ZP.
BMC Neurosci. 2012 Jan 4;13:2.
PMID: 22217148
Caltubin, a novel molluscan tubulin-interacting protein, promotes axonal growth and attenuates axonal degeneration of rodent neurons.
Nejatbakhsh N, Guo CH, Lu TZ, Pei L, Smit AB, Sun HS, van Kesteren RE,Feng ZP.
J Neurosci. 2011 Oct 26;31(43):15231-44.
PMID: 22031869
Syntaxin-1A inhibits KATP channels by interacting with specific conserved motifs within sulfonylurea receptor 2A.
Chao C, Liang T, Kang Y, Lin X, Xie H, Feng ZP, Gaisano HY.
J Mol Cell Cardiol. 2011 Nov;51(5):790-802.
PMID: 21884702
Differential regulation of low and high voltage-activated calcium channels in neonatal rat myocytes following chronic PKA modulation.
Hui K, Arnot M, Shin HS, Sun HS, Feng ZP.
Channels (Austin). 2011 Jul-Aug;5(4):357-66.
PMID: 21829086
Calcium binding protein-mediated regulation of voltage-gated calcium channels linked to human diseases.
Nejatbakhsh N, Feng ZP.
Acta Pharmacol Sin. 2011 Jun;32(6):741-8.
PMID: 21642945
Current understanding of K ATP channels in neonatal diseases: focus on insulin secretion disorders.
Quan Y, Barszczyk A, Feng ZP, Sun HS.
Acta Pharmacol Sin. 2011 Jun;32(6):765-80.
PMID: 21602835
Syntaxin-1A interacts with distinct domains within nucleotide-binding folds of sulfonylurea receptor 1 to inhibit beta-cell ATP-sensitive potassium channels.
Chang N, Liang T, Lin X, Kang Y, Xie H, Feng ZP, Gaisano HY.
J Biol Chem. 2011 Jul 1;286(26):23308-18.
PMID: 21540180
Expression, phosphorylation, and glycosylation of CNS proteins in aversive operant conditioning associated memory in Lymnaea stagnalis.
Silverman-Gavrila LB, Senzel AG, Charlton MP, Feng ZP.
Neuroscience. 2011 Jul 14;186:94-109.
PMID: 21530618
A sodium leak current regulates pacemaker activity of adult central pattern generator neurons in Lymnaea stagnalis.
Lu TZ, Feng ZP.
PLoS One. 2011 Apr 19;6(4):e18745.
PMID: 21526173
De novo protein synthesis of syntaxin-1 and dynamin-1 in long-term memory formation requires CREB1 gene transcription in Lymnaea stagnalis.
Guo CH, Senzel A, Li K, Feng ZP.
Behav Genet. 2010 Sep;40(5):680-93.
PMID: 20563839
Multifaceted role of heat shock protein 70 in neurons.
Lu TZ, Quan Y, Feng ZP.
Mol Neurobiol. 2010 Oct;42(2):114-23.
PMID: 20354811
Transcriptome analysis of the central nervous system of the mollusc Lymnaea stagnalis.
Feng ZP, Zhang Z, van Kesteren RE, Straub VA, van Nierop P, Jin K, Nejatbakhsh N, Goldberg JI, Spencer GE, Yeoman MS, Wildering W, Coorssen JR, Croll RP, Buck LT, Syed NI, Smit AB.
BMC Genomics. 2009 Sep 23;10:451.
PMID: 19775440
Neural phosphoproteomics of a chronic hypoxia model--Lymnaea stagnalis.
Silverman-Gavrila LB, Lu TZ, Prashad RC, Nejatbakhsh N, Charlton MP, Feng ZP.
Neuroscience. 2009 Jun 30;161(2):621-34.
PMID: 19324076
A method for identifying viable and damaged neurons in adult mouse brain slices.
Sun HS, French RJ, Feng ZP.
Acta Histochem. 2009;111(6):531-7.
PMID: 19203782
Differential sensitivities of CaV1.2 IIS5-S6 mutants to 1,4-dihydropyridine analogs.
Hui K, Kwok TC, Kostelecki W, Leen J, Roy PJ, Feng ZP.
Eur J Pharmacol. 2009 Jan 14;602(2-3):255-61.
PMID: 19068212
A genetic screen for dihydropyridine (DHP)-resistant worms reveals new residues required for DHP-blockage of mammalian calcium channels.
Kwok TC, Hui K, Kostelecki W, Ricker N, Selman G, Feng ZP, Roy PJ.
PLoS Genet. 2008 May 9;4(5):e1000067.
PMID: 18464914
Chronic hypoxia-induced alteration of presynaptic protein profiles and neurobehavioral dysfunction are averted by supplemental oxygen in Lymnaea stagnalis.
Fei GH, Feng ZP.
Neuroscience. 2008 Apr 22;153(1):318-28.
PMID: 18343591
NCS-1 differentially regulates growth cone and somata calcium channels in Lymnaea neurons.
Hui K, Feng ZP.
Eur J Neurosci. 2008 Feb;27(3):631-43.
PMID: 18279316
HSP70 reduces chronic hypoxia-induced neural suppression via regulating expression of syntaxin.
Fei G, Guo C, Sun HS, Feng ZP.
Adv Exp Med Biol. 2008;605:35-40.
PMID: 18085243
Neuronal calcium sensor-1 modulation of optimal calcium level for neurite outgrowth.
Hui K, Fei GH, Saab BJ, Su J, Roder JC, Feng ZP.
Development. 2007 Dec;134(24):4479-89.
PMID: 18039973
Zn2+ sensitivity of high- and low-voltage activated calcium channels.
Sun HS, Hui K, Lee DW, Feng ZP.
Biophys J. 2007 Aug 15;93(4):1175-83.
PMID: 17526568
The role of synaptotagmin I C2A calcium-binding domain in synaptic vesicle clustering during synapse formation.
Gardzinski P, Lee DW, Fei GH, Hui K, Huang GJ, Sun HS, Feng ZP.
J Physiol. 2007 May 15;581(Pt 1):75-90.
PMID: 17317745
Chronic hypoxia stress-induced differential modulation of heat-shock protein 70 and presynaptic proteins.
Fei G, Guo C, Sun HS, Feng ZP.
J Neurochem. 2007 Jan;100(1):50-61.
PMID: 17227434
Permeable ions differentially affect gating kinetics and unitary conductance of L-type calcium channels.
Hui K, Gardzinski P, Sun HS, Backx PH, Feng ZP.
Biochem Biophys Res Commun. 2005 Dec 16;338(2):783-92.
PMID: 16243294
Biophysical properties of menthol-activated cold receptor TRPM8 channels.
Hui K, Guo Y, Feng ZP.
Biochem Biophys Res Commun. 2005 Jul 29;333(2):374-82.
PMID: 15950184